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Recombinant Human CD200R1 protein,Fc,Myc,His

Cat NoADMD-056
Conjugate
Type重组蛋白
SourceHEK293
TagFc,Myc,His
Size1mg
ApplicationImmunology
FormatLiquid
Purity>95 %, SDS-PAGE
ConcentrationPlease refer to the vial lable for the specific concentration.
BufferSupplied in PBS
SpeciesHuman
StorageStore at -20 degree. Avoid repeated freeze/thaw cycles.
SynonymsCD200R, CD200R1, CRTR2, HCRTR2, MOX2R, OX2R
PurificationProtein A/G
NoteFor research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals.
MolecularWeight55.3 kDa
Description
BackgroundCD200R1 encodes a receptor for the OX-2 membrane glycoprotein, an Ig superfamily transmembrane glycoprotein expressed on the surface of myeloid cells; it can also be induced in certain T-cell subsets. CD200R1 interacts with CD200, which is also an Ig superfamily transmembrane glycoprotein, to down regulate myeloid cell functions. Mouse studies of a related gene suggest that this interaction may control myeloid function in a tissue-specific manner. CD200 is expressed on the surface of a variety of cells including neurons, epithelial cells, endothelial cells, fibroblasts, lymphoid cells, and astrocytes. The regulation of CD200R1 signaling can occur by posttranslational modification—namely, phosphorylation of tyrosines in the CD200R1 cytoplasmic tail—or by the inducible expression or downregulation of either CD200R1 or CD200.
We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC, Biotin, Alexa Fluor, Rhodamine B, Cy, Co-Au.