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Cat No | ADMD-063 |
Conjugate | |
Type | 重组蛋白 |
Source | HEK293 |
Tag | Myc,His |
Size | 1mg |
Application | Immunology |
Format | Liquid |
Purity | >95 %, SDS-PAGE |
Concentration | Please refer to the vial lable for the specific concentration. |
Buffer | Supplied in PBS |
Species | Human |
Storage | Store at -20 degree. Avoid repeated freeze/thaw cycles. |
Synonyms | CD66b, CD67, CEACAM8, CGM6, NCA-95 |
Purification | Protein A/G |
Note | For research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. |
MolecularWeight | 33.9 kDa |
Description | |
Background | A glycosylphosphatidyl-inositol-(GPI)-anchored glycoprotein, carcinoembryonic antigen (CEA)-related cell adhesion molecule 8 (CEACAM8), also known as CD66b, NCA-95 and CD67, was identified in human neutrophils. It is solely expressed by granulocytes, of which 95% are polymorphonuclear neutrophils (PMN). CEACAM8 is cell-adhesion proteins on neutrophils that belong to the human carcinoembryonic antigen (CEA) family. CEA family members are believed to function as intercellular adhesion molecules in vitro. CEACAM8 has been shown to adhere to the closely related molecule CEACAM6 (NCA-50/90 and CD66c), suggesting a role in the interaction between granulocytes or between granulocytes and epithelial cells expressing CEACAM6 in vivo. |