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Cat No | ADMD-064 |
Conjugate | |
Type | 重组蛋白 |
Source | HEK293 |
Tag | Fc,Myc,His |
Size | 1mg |
Application | Immunology |
Format | Liquid |
Purity | >95?%, SDS-PAGE |
Concentration | Please refer to the vial lable for the specific concentration. |
Buffer | Supplied in PBS |
Species | Human |
Storage | Store at -20 degree. Avoid repeated freeze/thaw cycles. |
Synonyms | CD152, CELIAC3, CTLA4, CTLA-4, GRD4, GSE, IDDM12 |
Purification | Protein A/G |
Note | For research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. |
MolecularWeight | 42 kDa |
Description | |
Background | CTLA-4, also known as CD152, belonging to the immunoglobulin superfamily, is primarily found on activated T cells and regulatory T cells (Tregs). CTLA-4 is closely related to the T-cell costimulatory CD28, and both molecules bind to B7-1 and B7-2 on antigen-presenting cells. CTLA-4 acts as a negative regulatory molecule of T-cell responses. Besides the full-length transmembrane form, CTLA-4 also exists in a truncated soluble form (sCTLA-4). |