Recombinant Human TL1A/TNFSF15 protein,His-Recombinant Protein-Biotyscience

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Recombinant Human TL1A/TNFSF15 protein,His

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Cat No	ADMD-084
Conjugate
Type	重组蛋白
Source	HEK293
Tag	His
Size	1mg
Application	Immunology
Format	Liquid
Purity	>95?%, SDS-PAGE
Concentration	Please refer to the vial lable for the specific concentration.
Buffer	Supplied in PBS
Species	Human
Storage	Store at -20 degree. Avoid repeated freeze/thaw cycles.
Synonyms	TL1, TL1A, TNFSF15, VEGI, VEGI192A
Purification	Protein A/G
Note	For research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals.
MolecularWeight	21.5 kDa
Description
Background	Tumor necrosis factor ligand superfamily member 15 (TNFSF15) is also named as TL1 and VEGI. And it belongs to the tumor necrosis factor family. It is a receptor for TNFRSF25 and TNFRSF6B. VEGI induced degradation of IκB alpha, and nuclear translocation of p65 subunit of NFκB by activating NFκB. TL1A mediates activation and apoptosis of NFκB in DR3-expressing cell lines. Overexpression by cancer cells of a secretable VEGI fusion protein resulted in abrogation of xenograft tumor progression. The isoforms show endothelial cell-specific expression and are generated from a 17 kb human gene by alternative splicing. In addition, VEGI can inhibit vascular endothelial growth and angiogenesis (in vitro).

We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC, Biotin, Alexa Fluor, Rhodamine B, Cy, Co-Au.

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Recombinant Human TL1A/TNFSF15 protein,His