Recombinant Mouse CD47/IAP/OA3 Protein(aa 19-158), His-Recombinant Protein-Biotyscience

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Recombinant Mouse CD47/IAP/OA3 Protein(aa 19-158), His

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Cat No	BIOP2291
Conjugate
Type	免疫检查点
Source	HEK293
Tag	His
Size	10 ug
Application	Immunogen
Format	Lyophilized
Concentration	Please refer to the vial lable for the specific concentration.
Buffer	Supplied in PBS, pH 7.4.
Species	Mouse
Storage	Store at –20 degree. Avoid repeated freeze/thaw cycles.
Synonyms	Leukocyte Surface Antigen CD47;Antigenic Surface Determinant Protein OA3;Integrin-AssociatedProtein;IAP;Protein MER6;CD47;MER6
Purification	> 95% by SDS-PAGE.
MolecularWeight
Description	aa 19-158
Background	CD47, also known as Integrin?Associated Protein (IAP) and OA3, is a glycosylated atypical member of theimmunoglobulin superfamily. Mouse CD47 is an integral membrane protein that consists of a extracellulardomain (ECD) with a single Ig?like domain, five membrane-spanning regions with short intervening loops, andC?terminal cytoplasmic tail. CD47 has a role in both cell adhesion by acting as an adhesion receptor for THBS1on platelets, and in the modulation of integrins. It plays an important role in memory formation and synapticplasticity in the hippocampus. As a receptor for SIRPA, it binding to which prevents maturation of immaturedendritic cells and inhibits cytokine production by mature dendritic cells. Interaction with SIRPG mediatescellcell adhesion, it enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cellactivation. It may play a role in membrane transport and/or integrin dependent signal transduction. It alsoprevents premature elimination of red blood cells.

We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC, Biotin, Alexa Fluor, Rhodamine B, Cy, Co-Au.

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Recombinant Mouse CD47/IAP/OA3 Protein(aa 19-158), His