Recombinant Human Urokinase/PLAU Protein(aa 1-431), His-Recombinant Protein-Biotyscience

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Recombinant Human Urokinase/PLAU Protein(aa 1-431), His

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Cat No	BIOP2455
Conjugate
Type	其他蛋白
Source	HEK293
Tag	His
Size	10 ug
Application	Immunogen
Format	Liquid
Concentration	Please refer to the vial lable for the specific concentration.
Buffer	Supplied in 20mM HEPES, 150mM NaCl, 2mM CaCl, 10% Glycerol, pH 7.5
Species	Human
Storage	Store at –20 degree. Avoid repeated freeze/thaw cycles.
Synonyms	ATF;BDPLT5;QPD;u-PA;UPA;URK
Purification	> 97% by SDS-PAGE.
MolecularWeight
Description	aa 1-431
Background	Plasminogen activator, urokinase, also known as PLAU and uPA, is a serine protease which converts plasminogen to plasmin, a broad-spectrum protease active on extracellular matrix (ECM) components. It is involved in complement activation, cell migration, wound healing, and generation of localized extracellular proteolysis during tissue remodelling, pro-hormone conversion, carcinogenesis and neoplasia. uPA and its receptor (uPAR) have been implicated in a broad spectrum of pathophysiological processes, including fibrinolysis, proteolysis, inflammation, atherogenesis and plaque destabilization, all of which are involved in the pathogenesis of MI (myocardial infarction). The role of uPA is not only does it as a kind of enzyme, but also is breast cancer, stomach cancer, colon cancer, bladder cancer, ovarian cancer, brain, and endometrial cancer markers for a strong invasion and metastasis.Because of the causal involvment of uPA in cancer invasion and metastasis, the blockade of uPA interactions and activity with specific inhibitors is of interest for novel strategies in cancer therapy.

We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC, Biotin, Alexa Fluor, Rhodamine B, Cy, Co-Au.

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Recombinant Human Urokinase/PLAU Protein(aa 1-431), His