Recombinant Human FZD4/CD344/EVR1 Protein, hFc-His-Recombinant Protein-Biotyscience

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Recombinant Human FZD4/CD344/EVR1 Protein, hFc-His

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Cat No	BIOP2723
Conjugate
Type	生物标志物
Source	HEK293
Tag	hFc-His
Size	20 ug
Application	Immunogen
Format	Lyophilized
Concentration	Please refer to the vial lable for the specific concentration.
Buffer	Supplied in PBS, pH 7.4.
Species	Human
Storage	Store at –20 degree. Avoid repeated freeze/thaw cycles.
Synonyms	FZD4;Frizzled-4;CD344;hFz4
Purification	> 95% by SDS-PAGE.
MolecularWeight
Description
Background	Frizzled-4 (FZD4) is also known as FzE4, CD344, which belongs to the G-protein coupled receptor Fz/Smo family. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes.Familial exudative vitreoretinopathy (FEVR) is a hereditary blinding disorder that features defects in retinal vascular development. Mutations in FZD4 are known to cause autosomal dominant exudative vitreoretinopathy (EVR1). The mutations in FZD4 are associated with the phenotypes of retinal folds or ectopic macula in FEVR.

We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC, Biotin, Alexa Fluor, Rhodamine B, Cy, Co-Au.

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Recombinant Human FZD4/CD344/EVR1 Protein, hFc-His