Recombinant Mouse B7-H3/CD276 Protein(aa 29-244), His-Recombinant Protein-Biotyscience

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Recombinant Mouse B7-H3/CD276 Protein(aa 29-244), His

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Cat No	BIOP2928
Conjugate
Type	生物标志物
Source	HEK293
Tag	His
Size	10 ug
Application	Immunogen
Format	Lyophilized
Concentration	Please refer to the vial lable for the specific concentration.
Buffer	Supplied in PBS, pH 7.4.
Species	Mouse
Storage	Store at –20 degree. Avoid repeated freeze/thaw cycles.
Synonyms	CD276 antigen;CD276;B7 homolog 3;B7-H3;CD276
Purification	> 95% by SDS-PAGE.
MolecularWeight
Description	aa 29-244
Background	CD276, also known as B7-H3, is a member of the B7 superfamily with signature IgV and IgG regions inextracellular domains. It is a type I transmembrane protein and shares 20–27% amino acid identity with otherB7 family members. B7-H3 is involved in the activation of T lymphocytes, and regulates murine boneformation. It is also reported that B7-H3 may play an important role in muscle-immune interactions, providingfurther evidence of the active role of muscle cells in local immunoregulatory processes. B7-H3 is expressed onT-cells, natural killer cells, and antigen presenting cells, as well as some non-immune cells, such as osteoblasts,fibroblasts, fibroblast-like synoviocytes and epithelial cells. High expression of B7-H3 in tumor vasculature alsocorrelates with poor survival in patients, suggesting that it may play a role in tumor cell migration.

We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC, Biotin, Alexa Fluor, Rhodamine B, Cy, Co-Au.

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Recombinant Mouse B7-H3/CD276 Protein(aa 29-244), His