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Cat No | BIOP3137 |
Conjugate | |
Type | 生长因子 |
Source | E. coli |
Tag | His |
Size | 10 ug |
Application | Immunogen |
Format | Lyophilized |
Concentration | Please refer to the vial lable for the specific concentration. |
Buffer | Supplied in 20mM PIPES, 500mM NaCl, pH 6.0. |
Species | Human |
Storage | Store at –20 degree. Avoid repeated freeze/thaw cycles. |
Synonyms | ARMET;ARP |
Purification | > 92% by SDS-PAGE. |
MolecularWeight | |
Description | aa 25-182 |
Background | The protein is localized in the endoplasmic reticulum (ER) and golgi, and is also secreted. Reducing this protein increases susceptibility to ER stress-induced death and results in cell proliferation. Activity of this protein is important in promoting the survival of dopaminergic neurons. The presence of polymorphisms in the N-terminal arginine-rich region, including a specific mutation that changes an ATG start codon to AGG, have been reported in a variety of solid tumors; however, these polymorphisms were later shown to exist in normal tissues and are thus no longer thought to be tumor-related. |