Recombinant Human FGFR3/CD333 Protein(aa 23-375), Fc-His-Recombinant Protein-Biotyscience

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Recombinant Human FGFR3/CD333 Protein(aa 23-375), Fc-His

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Cat No	BIOP3152
Conjugate
Type	生长因子
Source	HEK293
Tag	Fc-His
Size	20 ug
Application	Immunogen
Format	Lyophilized
Concentration	Please refer to the vial lable for the specific concentration.
Buffer	Supplied in PBS, pH 7.4.
Species	Human
Storage	Store at –20 degree. Avoid repeated freeze/thaw cycles.
Synonyms	ACH;CD333;CEK2;HSFGFR3EX;JTK4
Purification	> 90% by SDS-PAGE.
MolecularWeight
Description	aa 23-375
Background	FGFR3, also known as CD333, is a member of the fibroblast growth factor receptor (FGFR) family, with its amino acid sequence being highly conserved between members and among divergent species. FGFR family members differ from one another in their ligand affinities and tissue distribution. FGFRs are transmembrane catalytic receptors that have intracellular tyrosine kinase activity. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds acidic and basic fibroblast growth hormone and plays a role in bone development and maintenance. Mutations in FGFR3 gene lead to craniosynostosis and multiple types of skeletal dysplasia.

We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC, Biotin, Alexa Fluor, Rhodamine B, Cy, Co-Au.

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Recombinant Human FGFR3/CD333 Protein(aa 23-375), Fc-His