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Recombinant Mouse beta-NGF/β-NGF Protein(aa 122-241)

Cat NoBIOP3190
Conjugate
Type生长因子
SourceE. coli
Size10 ug
ApplicationImmunogen
FormatLyophilized
ConcentrationPlease refer to the vial lable for the specific concentration.
BufferSupplied in 20mM Tris,150mM NaCl,pH 8.0.
SpeciesMouse
StorageStore at –20 degree. Avoid repeated freeze/thaw cycles.
SynonymsBeta-Nerve Growth Factor;Beta-NGF;NGF;NGFB
Purification> 95% by SDS-PAGE.
MolecularWeight
Descriptionaa 122-241
BackgroundNGF is the first member discovered in the Neurotrophin family, which includes brain-derived neurotrophicfactor (BDNF), neurotrophin-3 (NT-3), and neurotrophin-4 (NT-4). These proteins belong to the cysteine-knotfamily of growth factors that assume stable dimeric structures. Mouse beta -NGF is a homodimer of two 120amino acid polypeptides. It shares approximately 90% homology at the amino acid level with human beta -NGFand 95.8% with rat beta -NGF. NGF signaling has been shown to play an important role in neuroprotection andrepair. β-NGF acts as a growth and differentiation factor for B lymphocytes, and enhances B-cell survival. It is apotent neurotrophic factor that signals through its receptor β -NGFR, and plays a crucial role in thedevelopment and preservation of the sensory and sympathetic nervous systems.
We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC, Biotin, Alexa Fluor, Rhodamine B, Cy, Co-Au.