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Cat No | BIOP3407 |
Conjugate | |
Type | 细胞因子 |
Source | E. coli |
Tag | His |
Size | 10 ug |
Application | Immunogen |
Format | Lyophilized |
Concentration | Please refer to the vial lable for the specific concentration. |
Buffer | Supplied in 20mM PB,150mM NaCl,pH 7.4. |
Species | Human |
Storage | Store at –20 degree. Avoid repeated freeze/thaw cycles. |
Synonyms | C-C Motif Chemokine 18;Alternative Macrophage Activation-Associated CC Chemokine 1;AMAC-1;CC Chemokine PARC;Dendritic Cell Chemokine 1;DC-CK1;Macrophage Inflammatory Protein4;MIP-4;Pulmonary and Activation-Regulated Chemokine;Small-Inducible Cyto |
Purification | > 95% by SDS-PAGE. |
MolecularWeight | |
Description | aa 21-89 |
Background | C-C Motif Chemokine 18 (CCL18) is secreted protein that belongs to the intercrine beta (chemokine CC) family.CCL18 is expressed at high levels in the lung, lymph nodes, placenta, bone marrow, and dendritic cells. CCL18 isa chemotactic factor that attracts lymphocytes but not monocytes or granulocytes. CCL18 is a novel CCchemokine that is highly homologous to MIP-1 alpha. CCL18 may be involved in B-cell migration into B-cellfollicles in lymph nodes. CCL18 attracts naive T-lymphocytes toward dendritic cells and activated macrophagesin lymph nodes. It has chemotactic activity for naive T-cells, CD4+ and CD8+ T-cells and thus may play a role inboth humoral and cell-mediated immunity responses. |