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Cat No | BIOP3416 |
Conjugate | |
Type | 细胞因子 |
Source | HEK293 |
Tag | His |
Size | 10 ug |
Application | Immunogen |
Format | Lyophilized |
Concentration | Please refer to the vial lable for the specific concentration. |
Buffer | Supplied in 20mM PB,150mM NaCl,pH7.2. |
Species | Human |
Storage | Store at –20 degree. Avoid repeated freeze/thaw cycles. |
Synonyms | High Mobility Group Protein B2;High Mobility Group Protein 2;HMG-2;HMGB2;HMG2 |
Purification | > 95% by SDS-PAGE. |
MolecularWeight | |
Description | aa 2-209 |
Background | High Mobility Group Protein B2 (HMGB2) belongs to the non-histone chromosomal high-mobility groupprotein family. Members of this family are chromatin-associated and widely spread in the nucleus of highereukaryotic cells. HMGB2 contains 2 HMG box DNA-binding domains. It is associated with chromatin and hasthe ability to bend DNA, preferentially single-stranded DNA. It is shown that HMGB2 is able to efficiently bendDNA and form DNA circles. In addition, HMGB2 is involved in the final ligation step in DNA end-joiningprocesses of DNA double-strand breaks repair and V(D)J recombination. |