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Recombinant Human HMGB2/High mobility group protein B2 Protein(aa 2-209), His

Cat NoBIOP3416
Conjugate
Type细胞因子
SourceHEK293
TagHis
Size10 ug
ApplicationImmunogen
FormatLyophilized
ConcentrationPlease refer to the vial lable for the specific concentration.
BufferSupplied in 20mM PB,150mM NaCl,pH7.2.
SpeciesHuman
StorageStore at –20 degree. Avoid repeated freeze/thaw cycles.
SynonymsHigh Mobility Group Protein B2;High Mobility Group Protein 2;HMG-2;HMGB2;HMG2
Purification> 95% by SDS-PAGE.
MolecularWeight
Descriptionaa 2-209
BackgroundHigh Mobility Group Protein B2 (HMGB2) belongs to the non-histone chromosomal high-mobility groupprotein family. Members of this family are chromatin-associated and widely spread in the nucleus of highereukaryotic cells. HMGB2 contains 2 HMG box DNA-binding domains. It is associated with chromatin and hasthe ability to bend DNA, preferentially single-stranded DNA. It is shown that HMGB2 is able to efficiently bendDNA and form DNA circles. In addition, HMGB2 is involved in the final ligation step in DNA end-joiningprocesses of DNA double-strand breaks repair and V(D)J recombination.
We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC, Biotin, Alexa Fluor, Rhodamine B, Cy, Co-Au.