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Cat No | BIOP3417 |
Conjugate | |
Type | 细胞因子 |
Source | HEK293 |
Tag | His |
Size | 10 ug |
Application | Immunogen |
Format | Lyophilized |
Concentration | Please refer to the vial lable for the specific concentration. |
Buffer | Supplied in 20mM PB,150mM NaCl,pH 7.4. |
Species | Human |
Storage | Store at –20 degree. Avoid repeated freeze/thaw cycles. |
Synonyms | Granulocyte-Macrophage Colony-Stimulating Factor Receptor Subunit Alpha;GM-CSF-R-Alpha;GMCSFR-Alpha;GMR-Alpha;CDw116;CD116;CSF2RA;CSF2R;CSF2RY |
Purification | > 95% by SDS-PAGE. |
MolecularWeight | |
Description | aa 23-320 |
Background | Granulocyte-Macrophage Colony-Stimulating Factor Receptor Subunit α (CSF2RA) is a single-pass type Imembrane protein which belongs to the type I cytokine receptor family of Type 5 subfamily. The CSF2RA geneis found in the pseudoautosomal region (PAR) of the X and Y chromosomes with some of the isoforms beingmembrane-bound and others being soluble. CSF2RA is a low affinity receptor for granulocyte-macrophagecolony-stimulating factor. CSF2RA transduces a signal that results in the proliferation, differentiation, andfunctional activation of hematopoietic cells. Defects in CSF2RA are the cause of pulmonary surfactantmetabolism dysfunction type 4 (SMDP4). |