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Cat No | BIOP3507 |
Conjugate | |
Type | 药物靶点 |
Source | HEK293 |
Tag | His |
Size | 100 ug |
Application | Immunogen |
Format | Lyophilized |
Concentration | Please refer to the vial lable for the specific concentration. |
Buffer | Supplied in PBS, pH 7.4. |
Species | Human |
Storage | Store at –20 degree. Avoid repeated freeze/thaw cycles. |
Synonyms | CD124;IL-4RA;IL4RA |
Purification | > 87% by SDS-PAGE. |
MolecularWeight | |
Description | aa 24-232 |
Background | This protein is alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE production. The encoded protein also can bind interleukin 4 to promote differentiation of Th2 cells. A soluble form of the encoded protein can be produced by proteolysis of the membrane-bound protein, and this soluble form can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells. |