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Cat No | BSA-1047 |
Conjugate | |
Type | 重组蛋白 |
Source | HEK293 |
Tag | His |
Size | 1mg |
Application | Immunology |
Purity | > 90%, SDS-PAGE |
Concentration | Please refer to the vial lable for the specific concentration. |
Buffer | Supplied in PBS. |
Storage | Store at -20 degree for long time. Avoid repeated freeze/thaw cycles. |
Synonyms | C-kitligand;DCUA;FPH2;FPHH;Kitl;KL-1;MGF;SCF;SF;SHEP7 |
Purification | Chromatography |
MolecularWeight | 19.3kD |
Description | 内毒素< 0.1 EU/ug |
Background | The SCF (Skpl-Cullin-F-box) complex is one of the Cullin-RING ubiquitin ligase (Cullin-RINGLigaseCRL) family. It is most commonly characterized by a RING finger domain (Ringfingerdomain), where E2 enzyme and substrate bind to the finger ring domain, catalyzing the transfer of ubiquitin molecule. E3 enzyme activity depends on the stem and the binding site in this domain is linked to the E2 enzyme. The SCF complex is a key ligase involved in cell cycle regulation and is closely related to tumor development and development. |