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Rabbit Anti-Acetyl-Smad2/3 (Lys19) Polyclonal Antibody

Cat NoBSPA-0534
Conjugate
TypePolyclonal Antibody
SourceRabbit
Size1 mg
ApplicationIHC-P; WB
FormatLiquid
ConcentrationPlease refer to the vial lable for the specific concentration.
BufferSupplied in PBS.
StorageStore at -20 degree. Avoid repeted freeze/thaw cycl.
SynonymsJV18;MADH2;MADR2;JV18-1;hMAD-2;hSMAD2;LDS3;LDS1C;MADH3;JV15-2;HSPC193;HsT17436;Mothers against decapentaplegic homolog 2;MAD homolog 2;Mothers against DPP homolog 2;Mad-related protein 2;SMAD family member 2;SMAD 2;Smad2;JV15-2;SMAD 3;hMAD-2;SMAD 2
Purification
NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
MolecularWeight
Description
BackgroundReceptor-regulated SMAD that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription. May act as a tumor suppressor in colorectal carcinoma. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator.
We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC, Biotin, Alexa Fluor, Rhodamine B, Cy, Co-Au.