Biotyscience Inc
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info@biotyscience.com
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Cat No | BSPA-1141 |
Conjugate | |
Type | Polyclonal Antibody |
Source | Rabbit |
Size | 1 mg |
Application | ELISA; WB; IHC |
Format | Liquid |
Concentration | Please refer to the vial lable for the specific concentration. |
Buffer | Supplied in PBS. |
Species | Human |
Storage | Store at -20 degree. Avoid repeted freeze/thaw cycl. |
Synonyms | AVEN;Apoptosis, caspase activation inhibitor;PDCD12 |
Purification | |
Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
MolecularWeight | |
Description | |
Background | Aven binds to both Bcl-x and the caspase regulator Apaf-1,which can supported that Bcl-x inhibits cell death at a late step in the death pathway.Identified in a yeast two-hybrid screen,Aven inhibited the proteolytic activation of caspases in a cell-free extract and suppressed apoptosis induced by Apaf-1 plus caspase-9. Expressing highly in the testis, ovary, and thymus. |