Rabbit Anti-CCNE1 Polyclonal Antibody-Products-Biotyscience

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  - --|--|Conjugation Kit
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Rabbit Anti-CCNE1 Polyclonal Antibody

Description
Documentation
Citations

Cat No	BSPA-1531
Conjugate
Type	Polyclonal Antibody
Source	Rabbit
Size	1 mg
Application	ELISA; IHC
Format	Liquid
Concentration	Please refer to the vial lable for the specific concentration.
Buffer	Supplied in PBS.
Species	Human
Storage	Store at -20 degree. Avoid repeted freeze/thaw cycl.
Synonyms	CCNE1;CCNE;pCCNE1
Purification
Note	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
MolecularWeight
Description
Background	The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK2, whose activity is required for cell cycle G1/S transition. This protein accumulates at the G1-S phase boundary and is degraded as cells progress through S phase. Overexpression of this gene has been observed in many tumors, which results in chromosome instability, and thus may contribute to tumorigenesis. This protein was found to associate with, and be involved in, the phosphorylation of NPAT protein , which participates in cell-cycle regulated histone gene expression and plays a critical role in promoting cell-cycle progression in the absence of pRB.

We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC, Biotin, Alexa Fluor, Rhodamine B, Cy, Co-Au.

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Rabbit Anti-CCNE1 Polyclonal Antibody