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Rabbit Anti-DHCR24 Polyclonal Antibody

Cat NoBSPA-1766
Conjugate
TypePolyclonal Antibody
SourceRabbit
Size1 mg
ApplicationELISA; WB; IHC
FormatLiquid
ConcentrationPlease refer to the vial lable for the specific concentration.
BufferSupplied in PBS.
SpeciesHuman
StorageStore at -20 degree. Avoid repeted freeze/thaw cycl.
SynonymsDHCR24;24-dehydrocholesterol reductase;DCE;SELADIN1;Nbla03646;seladin-1;delta-sterol reductase;seladin 1;diminuto/dwarf1 homolog;selective AD indicator 1;desmosterol-to-cholesterol enzyme;3 beta-hydroxysterol delta 24-reductase;3-beta-hydroxysterol delta-24-reductase
Purification
NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
MolecularWeight
Description
BackgroundThis gene encodes a flavin adenine dinucleotide -dependent oxidoreductase which catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. The protein contains a leader sequence that directs it to the endoplasmic reticulum membrane. Missense mutations in this gene have been associated with desmosterolosis. Also, reduced expression of the gene occurs in the temporal cortex of Alzheimer disease patients and overexpression has been observed in adrenal gland cancer cells.
We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC, Biotin, Alexa Fluor, Rhodamine B, Cy, Co-Au.