Small molecule refers to a low molecular weight (< 900 daltons) non-peptide, organic compound that may regulate a biological process. Small molecules are common in our environment, from toxins and heavy metals to vitamins, hormones and drugs of abuse. Since the first tyrosine kinase inhibitor imatinib was approved to enter the market by the US Food and Drug Administration (FDA) in 2001, an increasing number of small-molecule targeted drugs have been developed for the treatment of malignancies.

The application of small molecules of monoclonal antibody technology has been more and more widely, the ability to detect these molecules is critical to drug discovery and development, and is seeking for therapeutic drug monitoring applications to personalize the drug doses. However, developing monoclonal antibodies that specifically bind small molecule targets and requiring a certain sensitivity remains challenging. Therefore, the technology of small molecule hapten carrier coupling and monoclonal antibody production provide strong technical support.

Previously Biotyscience produced a large of small molecules of MAb with high specificity, and high sensitivity, such as carbamazepine, marihuana compounds, pigments, ginsenosides, aconitine alkaloid, baicalin and so on, and developed a stable method as a sensitivity detection method. Biotyscience Inc. offers small molecule monoclonal antibody production service to meet your unique mAb production schedule and requirements.