Biotyscience Inc
E-mail biotyscience@gmail.com
info@biotyscience.com
Tel 400-669-8850
Cat No | AMY-002 |
Conjugate | |
Type | 单克隆抗体 |
Clone | 2B102 |
Source | Mouse |
Tag | Biotin |
Size | 100 ug |
Application | ELISA, WB, IHC |
Format | Lyophilized |
Concentration | Please refer to the vial lable for the specific concentration. |
Buffer | Lyophilized with PBS, pH 7.4, containing 0.02% sodium azide. |
Storage | The lyophilized product remains stable for up to 1 year at -20°C from the date of receipt. The reconstituted antibody can be stored for 2-3 weeks at 2-8°C or for up to 12 months at -20°C or below. Avoid repeated freezing and thawing cycles. |
Synonyms | Anti-Polyethylene glycol antibody, mAb, Mouse |
Purification | Affinity chromatography |
Note | Some reagents such as Tween-20, Triton X-100 and NP-40 interfere with the PEG antibody interaction due to structural similarity to PEG. Antibody solution should not contain such reagents in the assay of PEGylated molecules. |
MolecularWeight | |
Description | The product can detect the variety of PEGs such as PEG40K, PEG20K, PEG5K, PEG12, PEGylated drugs and PEG conjugates. |
Background | PEG (Polyethylene glycol) is a polyether compound with many applications from industrial manufacturing to medicine. PEGylation is a technology that covalently couples non-toxic, hydrophilic polyethylene glycol (PEG) to the drug. It is an FDA-approved method for the delivery of protein drugs. PEG modification can reduce the drug immunogenicity and antigenicity. PEGylated drug decelerates renal excretion, improves stability towards proteolysis and increases its half-life in blood. Accurate and sensitive quantification of PEG conjugates is important for PEG conjugated product development and pharmaceutical study. Polyethylene glycol (PEG) antibody is a useful tool for the detection of PEGylated molecules. |