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Mouse anti-Human PD-1/CD279 Monoclonal Antibody

Cat NoBMA-1833
Conjugate
TypeMonoclonal Antibody
SourceMouse
Size50 uL
ApplicationWB; IHC; IF; FC
FormatLiquid
ConcentrationPlease refer to the vial lable for the specific concentration.
BufferSupplied in PBS with 0.05% sodium azide,0.2% BSA,40% glycerol,pH7.4.
SpeciesHuman
StorageStore at -20℃. Avoid freeze / thaw cycles.
SynonymsPDCD1;CD279;PD-1;PD1;SLEB2;hPD-1;hPD-l;hSLE1
PurificationAffinity purification
MolecularWeightRefer to figures
Description
BackgroundThis gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases.
We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC, Biotin, Alexa Fluor, Rhodamine B, Cy, Co-Au.