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Monoclonal Antibody

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Rabbit anti-Human CD3E+CD3G Monoclonal Antibody

Cat NoBMA-1834
Conjugate
Type重组兔多抗
SourceRabbit
Size50 uL
ApplicationIHC
FormatLiquid
ConcentrationPlease refer to the vial lable for the specific concentration.
BufferSupplied in PBS with 0.02% thimerosal,0.05% BSA,pH7.3.
SpeciesHuman
StorageStore at 4℃. Avoid freeze / thaw cycles.
SynonymsCD3E;IMD18;T3E;TCRE;CD3e molecule;CD3G;CD3-GAMMA;IMD17;T3G
PurificationAffinity purification
MolecularWeightRefer to figures
Description
BackgroundThe protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. The protein encoded by this gene is the CD3-gamma polypeptide, which together with CD3-epsilon, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. Defects in this gene are associated with T cell immunodeficiency.
We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC, Biotin, Alexa Fluor, Rhodamine B, Cy, Co-Au.