Biotyscience Inc
E-mail biotyscience@gmail.com
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Cat No | BMA-869 |
Conjugate | |
Type | Monoclonal Antibody |
Source | Mouse |
Size | 50 uL |
Application | Immunogen |
Format | Liquid |
Concentration | Please refer to the vial lable for the specific concentration. |
Buffer | Supplied in PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |
Species | Human |
Storage | Store at -20℃. Avoid freeze / thaw cycles. |
Synonyms | PDCD1;CD279;PD-1;PD1;SLEB2;hPD-1;hPD-l;hSLE1 |
Purification | Affinity purification |
MolecularWeight | 52-65KDa |
Description | |
Background | This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases. |