Cyclic peptides are mainly derived from plants, fungi, Marine natural products and most biological organisms. Cyclic peptides are a class of compounds with special biological activity and strong pharmacological activity. Moreover, the structure of most cyclic peptides is more stable than that of straight chain peptides, and has the advantages of high fat solubility, strong membrane penetration and long half-life in vivo, so that cyclic peptides play an important role in anti-tumor, antiviral and natural fields.Compared with straight-chain peptides, cyclic peptides have better conformational stability, targeting affinity and selectivity. It has the characteristics of small molecule drugs and macromolecule organisms, such as high stability, high potency and high selectivity, and is a promising therapeutic drug.
Biotyscience offers a full range of services for cyclic peptide drug development, from high-throughput screening and optimization to CGMP-compliant manufacturing to simplify the transition of these compounds from laboratory concept to clinical application.
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Website: www.biotyscience.com Phone: + 400-669-8850 Email: biotyscience@gmail.com
We offer both disulfide and amide-bonded cyclic peptide synthesis services.We can perform cyclic peptide synthesis according to requirements, and different products have different purity specifications.
Disulfide cyclic peptide | Disulfide cyclic peptide Monodisulfide polypeptide Disulfide polypeptide Triple disulfide polypeptide Intermolecular symmetric disulfide polypeptides Intermolecular asymmetrical disulfide polypeptides A polypeptide formed by mercapto Mpa mercaptopropionic acid into disulfide bonds |
Amide-bonded cyclic peptide | A polypeptide in which the amide bond ends in a ring |
Polypeptides formed by amide side chains (Glu, Asp, Lys, Orn) |
Service Type | Sequence Length | Quantity | Purity Range | QC Reports Available | Additional Services |
Disulfide Bond (Up to three) | Evaluation is needed | μg to mg | ≥70% to ≥98% | MS, HPLC for cyclization verification | Endotoxin control & analysis Nitrogen analysis Amino acid analysis Moisture content analysis NMR analysis HPLC-UV-fluorescence TFA exchange Residual solvent testing and so on |
Click Chemistry | Up to 50 AA | ||||
Bicyclic Cyclic Peptide | |||||
Staple Peptides | |||||
Lactone |
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Website: en.biotyscience.com
Phone: +86-400-669-8850
Email: biotyscience@gmail.com