Recombinant Human ANTXR1 Protein(aa 33-321), His-Recombinant Protein-Biotyscience

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Recombinant Human ANTXR1 Protein(aa 33-321), His

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Cat No	BIOP2603
Conjugate
Type	其他蛋白
Source	Mammalian
Tag	His
Size	10 ug
Application	Immunogen
Format	Lyophilized
Concentration	Please refer to the vial lable for the specific concentration.
Buffer	Supplied in 20mM PB,150mM NaCl,pH 7.4.
Species	Human
Storage	Store at –20 degree. Avoid repeated freeze/thaw cycles.
Synonyms	Anthrax Toxin Receptor 1;Tumor Endothelial Marker 8;ANTXR1;ATR;TEM8
Purification	> 95% by SDS-PAGE.
MolecularWeight
Description	aa 33-321
Background	This protein is a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes. Three alternatively spliced variants that encode different protein isoforms have been described.

We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC, Biotin, Alexa Fluor, Rhodamine B, Cy, Co-Au.

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Recombinant Human ANTXR1 Protein(aa 33-321), His