Recombinant Human S100 Calcium Binding Protein B/S100B Protein(aa 1-92), His-Recombinant Protein-Biotyscience

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Recombinant Human S100 Calcium Binding Protein B/S100B Protein(aa 1-92), His

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Cat No	BIOP2604
Conjugate
Type	其他蛋白
Source	E. coli
Tag	His
Size	10 ug
Application	Immunogen
Format	Lyophilized
Concentration	Please refer to the vial lable for the specific concentration.
Buffer	Supplied in 20mM PBS,150mM NaCl,pH 7.4.
Species	Human
Storage	Store at –20 degree. Avoid repeated freeze/thaw cycles.
Synonyms	Protein S100-B;S-100 protein beta chain;S-100 protein subunit beta;S100 calcium-bindingprotein B;S100b;S100 beta;S100 calcium binding protein B
Purification	> 95% by SDS-PAGE.
MolecularWeight
Description	aa 1-92
Background	S100-B, is an acidic protein with a molecular weight of 21 kDa belonging to the S100 family. S100-B containstwo EF-hand-type calcium-binding motifs separated by a hinge region with a hydrophobic cleft. S100-B playsan important role in neurodevelopment, differentiation, and brain construction. S100-B has neuroprotectiveeffects, but at high concentrations S100-B is neurotoxic. Extracellular concentration of S100-B increasesfollowing brain damage, which easily penetrates into cerebrospinal fluid in brain damage and then into theblood. S100-B is expressed and produced by astrocytes in vertebrate brains and in the CNS, and the astrocytesare the major cells producing S100-B protein in gray matter, as well as oligodendrocytes are the predominantS100-B in protein producing cells in white matter. The major advantage of using S100-B is that elevations inserum or CSF levels provide a sensitive measure for determining CNS injury at the molecular level before grosschanges develop, enabling timely delivery of crucial medical intervention before irreversible damage occurs. Inaddition, S100-B, which is also present in human melanocytes, is a reliable marker for melanoma malignancyboth in bioptic tissue and in serum.

We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC, Biotin, Alexa Fluor, Rhodamine B, Cy, Co-Au.

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Recombinant Human S100 Calcium Binding Protein B/S100B Protein(aa 1-92), His