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Recombinant Human IGF1R Protein(aa 1-932), His

Cat NoBIOP3174
Conjugate
Type生长因子
SourceHEK293
TagHis
Size50 ug
ApplicationImmunogen
FormatLyophilized
ConcentrationPlease refer to the vial lable for the specific concentration.
BufferSupplied in PBS Buffer, pH 7.4.
SpeciesHuman
StorageStore at –20 degree. Avoid repeated freeze/thaw cycles.
SynonymsCD221;IGF-I R;IGF1 Receptor;IGFIR;IGFR;JTK13;IGF1R
Purification> 90 % by SDS-PAGE.
MolecularWeight
Descriptionaa 1-932
BackgroundThis receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC, Biotin, Alexa Fluor, Rhodamine B, Cy, Co-Au.