Recombinant Human ANGPTL4 Protein(aa 166-406), His-Recombinant Protein-Biotyscience

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Recombinant Human ANGPTL4 Protein(aa 166-406), His

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Cat No	BIOP3175
Conjugate
Type	生长因子
Source	Mammalian
Tag	His
Size	10 ug
Application	Immunogen
Format	Lyophilized
Concentration	Please refer to the vial lable for the specific concentration.
Buffer	Supplied in PBS, pH 7.4.
Species	Human
Storage	Store at –20 degree. Avoid repeated freeze/thaw cycles.
Synonyms	ARP4;FIAF;HARP;HFARP;NL2;PGAR;TGQTL;UNQ171;pp1158
Purification	> 95% by SDS-PAGE.
MolecularWeight
Description	aa 166-406
Background	Angiopoietin-related protein 4 （ ANGPTL4 ） is a secreted protein and contains 1 fibrinogen C-terminal domain. The protein may act as a regulator of angiogenesis and modulate tumorigenesis. It inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage. ANGPTL4 may exert a protective function on endothelial cells through an endocrine action. It is directly involved in regulating glucose homeostasis, lipid metabolism, and insulin sensitivity (By similarity). In response to hypoxia, the unprocessed form of the protein accumulates in the subendothelial extracellular matrix (ECM). The matrix-associated and immobilized unprocessed form limits the formation of actin stress fibers and focal contacts in the adhering endothelial cells and inhibits their adhesion. It also decreases motility of endothelial cells and inhibits the sprouting and tube formation.

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Recombinant Human ANGPTL4 Protein(aa 166-406), His